TACE plus Nexavar for unresectable HCC improves progression-free survival

Treatment with transarterial chemoembolization and Nexavar improved progression-free survival compared with transarterial chemoembolization alone in patients with unresectable hepatocellular carcinoma, according to a study published in Gut.Masatoshi Kudo, MD, PhD, from the Kindai University Faculty of Medicine in Japan, and colleagues explained that because of the high tumor recurrence rate after TACE, the procedure is…

Doptelet cost-effective, avoids transfusions for CLD-related thrombocytopenia

Treatment with Doptelet was cost-effective for the treatment of thrombocytopenia in patients with chronic liver diseases compared with other treatment options, according to data presented at the American Society of Hematology meeting.The study compared Doptelet (avatrombopag, Dova Pharmaceuticals), an oral thrombopoietin receptor agonist approved by both the FDA and the European Medicines Agency (EMA) for…

Patients with HCV responsive to alcohol intervention

Patients with current or prior hepatitis C infection were willing to engage in alcohol intervention including counseling and referral to treatment when encouraged by liver medical providers, according to data published in Hepatology.“Alcohol use in the setting of HCV infection is associated with increased rates of fibrosis progression, liver-related mortality, and overall mortality,” Rae Jean…

Endoscopic sleeve gastroplasty safe in children, adolescents

Endoscopic sleeve gastroplasty was found to be safe and effective in children and adolescents with obesity, according to data published in the American Journal of Gastroenterology.“We incorporated [endoscopic sleeve gastroplasty] into our standardized pediatric bariatric clinical pathway with a few modifications,” Aayed Alqahtani, MD, FRCSC, FACS, an associate professor of surgery at King Saud University…