News

GI symptoms plus loss of taste, smell, fever highly specific to COVID-19

While gastrointestinal symptoms like anorexia and diarrhea are common in both patients with COVID-19 and those without, these symptoms plus a loss of smell, taste and fever were 99% specific for COVID-19, according to a study published in Gastroenterology.“Current testing guidelines should highlight the symptoms of loss of smell, taste, fever, anorexia and diarrhea as…

News

No significant link found between biologics, melanoma development in inflammatory diseases

Patients treated with biologic therapy for inflammatory diseases may not have a higher risk for developing melanoma, a systematic review and meta-analysis found.Seven cohort studies, including more than 34,000 patients treated with biologics and more than 135,000 patients treated with systemic therapies, were analyzed in the review. Two studies involved patients with inflammatory bowel disease,…

News

Donafenib extends OS in advanced liver cancer

Donafenib conferred a modest but statistically significant OS improvement as first-line therapy for advanced hepatocellular carcinoma, according to study results presented during the ASCO20 Virtual Scientific Program.The novel multikinase inhibitor also exhibited a favorable safety and tolerability profile, results of the randomized phase 2/phase 3 trial showed.“Hepatocellular carcinoma is characterized by an insidious onset with…