Frailty nearly triples mortality odds in IBD

Frailty was independently associated with mortality in a large cohort of patients with inflammatory bowel disease, according to study results.Ashwin Ananthakrishnan, MD, of the division of gastroenterology at Massachusetts General Hospital, and colleagues wrote that improved treatments and increased global incidence mean that people with IBD are getting older.“Frailty may be particularly pertinent in chronic…

HHS finalizes rule it says protects civil rights; LGBTQ, women’s health advocates disagree

The HHS announced that it has finalized a rule that allows the government to interpret sex discrimination based on the definition of the word “sex” as male or female and biology — a move the agency also said “protects and enforces the civil rights of all.”However, medical societies argue that the rule weakens nondiscrimination protections…

VIDEO: GI societies join forces to promote diversity within the field

In this exclusive video, Bishr Omary, MD, PhD, the president of the American Gastroenterological Association and Henry Rutgers professor of biomedical sciences at Rutgers University, discussed the joint statement released by various GI societies including the AGA, American Association for the Study of Liver Disease, American College of Gastroenterology and American Society for Gastrointestinal Endoscopy….

FDA grants orphan drug status to DKN-01 for certain gastrointestinal cancers

The FDA granted orphan drug designation to DKN-01 for the treatment of gastric or gastroesophageal junction cancers.DKN-01 (Leap Therapeutics) is a humanized monoclonal antibody that blocks the activity of the Dickkopf-1 (DKK1) protein, a modulator of Wnt/Beta-catenin signaling.“Orphan drug designation for DKN-01 in gastric and gastroesophageal junction cancer is another significant milestone in our DKN-01…