Model predicts EoE even before histology

Using updated diagnostic guidelines, researchers developed a new model identify patients with eosinophilic esophagitis based on clinical features and endoscopic findings, according to study results.Evan S. Dellon, MD, MPH, of the Center for Esophageal Diseases and Swallowing at the University of North Carolina at Chapel Hill, and colleagues wrote that newer guidelines eliminated the requirement…

RAAS inhibitor use may reduce 3-year colorectal cancer risk in certain patients

Use of renin-angiotensin-aldosterone system, or RAAS, antagonists such as ACE inhibitors or angiotensin receptor blockers was linked to reduced risk for colorectal cancer in the 3 years after an index colonoscopy with negative diagnosis.For every year of ACE inhibitor or angiotensin receptor blocker use, researchers observed a 5% decrease in risk for colorectal cancer, up…

Hydroxychloroquine, azithromycin prescriptions skyrocket amid early days of COVID-19

Dispensed prescriptions of hydroxychloroquine in the U.S. increased 86.2%, while such prescriptions of chloroquine increased 158.6% from February to March 2020, data show.The report in JAMA Internal Medicine also showed that the percentage of patients receiving both hydroxychloroquine and azithromycin prescriptions increased 1,044% during the same time period.Nadine Shehab, PharmD, MPH, of the CDC’s COVID-19…

Biennial screening produces sustained mortality reduction in CRC

There was a sustained reduction in mortality among individuals who complied with biennial fecal occult blood test screening for colorectal cancer, according to research published in Clinical Gastroenterology and Hepatology.Aasma Shaukat, MD, MPH, of the division of gastroenterology at Minneapolis Veterans Affairs Health Care system, and colleagues wrote that previous research has shown that fecal…

Liquid biopsy shows promise for early detection of pancreatic cancer

A liquid biopsy has shown promise for the early detection and staging of pancreatic ductal adenocarcinoma.The test — developed by researchers at University of Pennsylvania’s Perelman School of Medicine, Abramson Cancer Center and School of Engineering and Applied Science — could play a valuable role in guiding treatment of the most common form of pancreatic…