RO7049389 is safe, well tolerated in chronic hepatitis B treatment

RO7049389 is safe, well tolerated in chronic hepatitis B treatment

Core protein allosteric modulator RO7049389 was safe and demonstrated antiviral activity in patients with chronic hepatitis B infection, according to research published in Lancet Gastroenterology and Hepatology.“Current treatment options for patients with chronic HBV infection comprise two classes of drugs: subcutaneously administered interferon preparations and orally administered nucleotide analogues. Neither treatment achieves a high rate…

IBD: Caring for your patients through life’s stages

IBD: Caring for your patients through life’s stages

Approximately 3.1 million Americans currently have inflammatory bowel diseases and as many as 70,000 new cases are diagnosed in the United States each year, according to the Crohn’s and Colitis Foundation.While the pathogenesis of IBD remains unclear, scientific evidence points toward an interaction between genetics, the immune system and environmental risk factors where unidentified environmental…

GIs should wear ‘internal medicine hats’ to care for IBD across all ages

GIs should wear ‘internal medicine hats’ to care for IBD across all ages

I remember being flummoxed as a first-year gastroenterology fellow when we had an elderly patient on service with abdominal pain and weight loss who ended up diagnosed with ileocolonic Crohn’s disease. Our “IBD antennae” are often finely tuned when we see a patient in their late teens or 20s with such symptoms, but maybe not…