Real-world data highlight patterns of cannabis use in IBD

Real-world data highlight patterns of cannabis use in IBD

Using real-world data, researchers identified patterns of use of medically dispensed cannabis in patients with inflammatory bowel disease, according to a poster presented at the ACG Annual Scientific Meeting.“We know that cannabis use in IBD patients is common and that many report improvement in IBD-related symptoms, including mitigation of pain,” Jami A.R. Kinnucan, MDFACG, assistant…

Initial choice of biologic may affect persistence of therapy in IBD

Initial choice of biologic may affect persistence of therapy in IBD

Among patients with inflammatory bowel disease who received at least two biologic therapies, discontinuation of treatment appeared to vary based on initial treatment choice, according to data presented at the ACG Annual Scientific Meeting.“Decisions about choice of biologic for treatment of moderate to severe Crohn’s disease and ulcerative colitis are complex, owing to limited data…

Q&A: Forthcoming tool will use genetics to help eliminate ‘diagnostic odyssey’

Q&A: Forthcoming tool will use genetics to help eliminate ‘diagnostic odyssey’

Geisinger Health System is working to develop a tool that it said will dramatically lower the time it takes to diagnose rare conditions with a genetic cause.The Pennsylvania-based health system said it received a $5 million grant from the NIH’s National Human Genome Research Institute for its work on the tool.Some of the diseases the…

Thyroid hormone receptor beta agonist may be safe, well tolerated in NASH

Thyroid hormone receptor beta agonist may be safe, well tolerated in NASH

Terns Pharmaceuticals announced positive top-line results from a phase 1 clinical trial of TERN-501, a thyroid hormone receptor beta agonist for the treatment of nonalcoholic steatohepatitis, according to a press release.“The goal of the phase 1 study is to evaluate the safety, tolerability pharmacodynamics and pharmacokinetics of TERN-501 in healthy volunteers,” D. Barry Crittenden, MD,…

More research needed on pancreatic cancer treatment strategies, expert says

More research needed on pancreatic cancer treatment strategies, expert says

Despite a significant amount of data in the adjuvant setting for pancreatic cancer, more research is needed to better define perioperative and neoadjuvant treatment strategies, according to a speaker at Chemotherapy Foundation Symposium.“We sorely need these trials so that we know better what to do for our patients with pancreatic cancer,” Kim A. Reiss, MD,…

Bariatric surgery provides ‘huge’ reduction in major adverse liver outcomes, CV events

Bariatric surgery provides ‘huge’ reduction in major adverse liver outcomes, CV events

Adults with nonalcoholic steatohepatitis and obesity have a much lower risk for a major adverse liver outcome or major adverse cardiovascular event if they undergo bariatric surgery vs. nonsurgical treatment, according to study data.In findings published in JAMA, a group of adults with NASH and obesity who underwent bariatric surgery had an 88% lower risk…

Obesity links to CRC among weight loss surgery, medication

Obesity links to CRC among weight loss surgery, medication

LAS VEGAS – Obesity was an independent risk factor for the development of colorectal cancer among patients who underwent weight loss surgery or who were on weight loss medication, according to a presentation.“Obesity prevalence is on the rise throughout the world and globally and has doubled over the last four decades,” Zryan Shwani, MD, of…

Sleeve gastrectomy, gastric bypass associated with similar quality of life improvements

Sleeve gastrectomy, gastric bypass associated with similar quality of life improvements

Adults with obesity who underwent bariatric surgery at a clinic in Turkey had similar improvements in quality of life, regardless whether they underwent a sleeve gastrectomy or Roux-en-Y gastric bypass, according to study data.“Bariatric surgery will continue to be at the forefront in the fight against obesity until such time as an alternative nonsurgical method…