FDA accepts supplemental biologics license application for Dupixent for EoE

FDA accepts supplemental biologics license application for Dupixent for EoE

Regeneron Pharmaceuticals Inc. and Sanofi announced that the FDA accepted for priority review a supplemental biologics license application for Dupixent 300 mg for adults and children aged 12 years and older with eosinophilic esophagitis.According to a release from the biotechnology companies, the application was supported by two phase 3 trials that assessed the efficacy and…

ACG updates guidance for diagnosis, management of Barrett’s esophagus

ACG updates guidance for diagnosis, management of Barrett’s esophagus

The ACG issued revised clinical guidelines for the diagnosis and management of patients with Barrett’s esophagus, which was published in the American Journal of Gastroenterology.The guidelines implement Grading of Recommendations, Assessment, Development and Evaluation (GRADE) methodology to propose 21 recommendations for the definition and diagnosis of BE, screening for both BE and esophageal adenocarcinoma (EAC),…

COVID-19 led to unprecedented decline in global life expectancy

COVID-19 led to unprecedented decline in global life expectancy

The COVID-19 pandemic reduced the world’s life expectancy by about 2 years, according to recent estimates published in Population and Development Review.“Since 1950, annual declines of that magnitude had only been observed on rare occasions, such as Cambodia in the 1970s, Rwanda in the 1990s, and possibly some sub-Saharan African nations at the peak of…