MRE plus FIB-4 bests MAST, FAST to ‘rule in or rule out’ stage 2 fibrosis in NAFLD

LONDON — Magnetic resonance elastography in combination with the fibrosis-4 index was a better predictor of significant fibrosis in patients with nonalcoholic fatty liver disease vs. other noninvasive techniques, noted a presenter here.“NALFD patients with significant fibrosis — defined as those who have stage 2 or higher — are candidates for pharmacological treatments,” Rohit Loomba,…

‘Entrenched’ racial disparities remain in health care

Racial inequities in health care have fluctuated in severity for decades but data show that one constant remains: the disparities persist.Samuel L. Dickman, MD, the medical director for primary care at Planned Parenthood South Texas, and colleagues sought to understand how much progress has been made in equalizing health care access in the United States…

Tislelizumab regimen extends OS in advanced esophageal cancer

The addition of tislelizumab to first-line chemotherapy extended OS among patients with advanced esophageal cancer, according to study results presented at European Society for Medical Oncology World Congress on Gastrointestinal Cancer.The combination conferred a significant survival benefit regardless of PD-L1 status, results of the randomized phase 3 RATIONALE 306 study showed.Tislelizumab (BGB-A317, BeiGene) is a…

Support vector machines lead machine learning models in predicting liver decompensation

LONDON — Support vector machines had the highest accuracy in predicting liver decompensation among a subset of patients in Germany compared with other machine learning models, according to data presented at the International Liver Congress.“Since decompensation of cirrhosis significantly increases mortality, early detection of patients at risk of worsening liver function is of paramount importance,”…