Electroacupuncture may improve opioid-induced constipation in patients with cancer

Electroacupuncture increased weekly spontaneous bowel movements and improved quality of life in patients with cancer and opioid-induced constipation, according to data published in JAMA Network Open.“Opioid-induced constipation (OIC) affects 60% to 90% of patients with cancer-related opioid use,” Weiming Wang, MD, PhD, of the department of acupuncture and moxibustion at Guang’anmen Hospital in Beijing, and…

FDA expands Livmarli label to include infants with pruritus aged 3 months old or older

The FDA has approved labeling changes for Livmarli, reducing the age of prescribing to infants with Alagille syndrome from 1 year to 3 months for the treatment of cholestatic pruritus, according to a Mirum Pharmaceuticals press release.Maralixibat (Livmarli, Mirum Pharmaceuticals), a once-daily ileal bile acid transporter inhibitor, was originally approved by the FDA in 2021…

Proton pump inhibitors improve survival in systemic sclerosis-associated ILD

The use of proton pump inhibitors improves overall and progression-free survival in patients with systemic sclerosis-associated interstitial lung disease, according to data published in Rheumatology.Meanwhile, the researchers additionally concluded that gastroesophageal reflux disease (GERD) has no impact on survival in either SSc or SSc-ILD.“GERD, which is frequently treated with proton-pump inhibitors (PPI), is common in…