Individuals with certain germline pathogenic variants had a substantially higher risk for developing gastric cancer after Helicobacter pylori infection, results of a Japan-based case-control study showed.The findings, published in The New England Journal of Medicine, suggest risk for gastric cancer is more heavily related to hereditary factors than previously thought, the investigators noted.Four of the…
Biweekly infusions of olamkicept 600 mg increased the likelihood of clinical response and mucosal healing at 12 weeks in patients with active ulcerative colitis compared with placebo, according to results published in JAMA.“Olamkicept, a first-in-class, selective inhibitor of the s-interleukin-6R/IL-6 complex, is a dimer formed by fusing two complete extracellular domains of gp130 to human…
SAN ANTONIO — A high proportion of patients with eosinophilic esophagitis also had simultaneous atopic or allergic comorbid conditions, according to data presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting.Eosinophilic esophagitis (EoE) is a chronic, progressive type II inflammatory disease, Marc E. Rothenberg, MD, PhD, director of the Cincinnati Center for…
Chemoradiotherapy with a contact X-ray brachytherapy boost significantly increased clinical complete response and 3-year organ preservation rates in patients with early cT2-cT3 rectal adenocarcinoma, particularly tumors smaller than 3 cm.“The standard of care for rectal cT2 to cT3 adenocarcinoma is radical proctectomy by total mesorectal excision, sometimes preceded by neoadjuvant chemoradiotherapy, external beam radiotherapy or…
The Florida Gastroenterologic Society was originally conceived in 1965 by James L. Borland, M.D., a well respected Gastroenterologist who practiced in Jacksonville, Florida.