First patient treated in Takeda’s phase 3 trial for alpha-1 antitrypsin deficiency
Arrowhead Pharmaceuticals announced that the first patient has been treated in Takeda Pharmaceuticals’ phase 3 clinical trial of fazirsiran for the treatment of alpha-1 antitrypsin deficiency associated liver disease.Fazirsiran, an investigational RNA interference therapy intended to reduce the production of the mutant alpha-1 antitrypsin protein, was co-developed by both Takeda and Arrowhead. The drug was…