Day: April 20, 2023

Combination therapy with adalimumab plus low-dose methotrexate induced a two-fold reduction of treatment failure among pediatric patients with Crohn’s disease, according to research published in Gastroenterology.“Tumor necrosis factor inhibitors (TNFi), including infliximab and adalimumab, are a mainstay of pediatric Crohn’s disease therapy; however, non-response and loss of response are common,” Michael D. Kappelman, MD, MPH,…

Meridian Bioscience has announced FDA 510(k) clearance of its Curian Shiga Toxin assay intended for detection and differentiation of Shiga toxin 1 and 2 within a single device, according to a company release.By adding Shiga toxin detection, the company has expanded the platform’s foodborne immunofluorescent testing capabilities beyond Campylobacter.“We are excited to continue the expansion…

President Joe Biden plans to nominate NCI Director Monica M. Bertagnolli, MD, FACS, FASCO, to serve as director of the NIH, according to published reports.Bertagnolli — a surgical oncologist who took the helm of NCI in October — would fill the role vacated in December 2021 by longtime NIH Director Francis S. Collins, MD, PhD.“In…

Adolescents and young adults with obesity who undergo sleeve gastrectomy have declines in bone strength and volumetric bone mineral density 1 year after surgery, according to study data.In findings published in The Journal of Bone and Mineral Research, young people with obesity who underwent sleeve gastrectomy lost a mean 34.3 kg of body weight 1…

In a Healio video exclusive, Sam Jactel, CEO and founder of Ayble Health, highlights how the symptom management mobile app could improve quality of life for patients with chronic gastrointestinal conditions.Jactel, himself an ulcerative colitis patient, said he created the app after he had a “rocky” experience with his own treatment. He had relapsed in…