Bile acid sequestrant relieves refractory GERD symptoms

Recently published study results showed that the bile acid sequestrant IW-3718 reduced heartburn and regurgitation symptoms in patients with refractory GERD.Further, the 1,500 mg twice-daily dose of IW-3718 (Ironwood Pharmaceuticals) showed the best results vs. placebo than the 500 mg and 1,000 mg doses.“The study showed that heartburn symptoms were significantly reduced in the group receiving 1,500 mg twice daily, compared to the placebo group,” Michael F. Vaezi, MD, PhD, of Vanderbilt University Medical Center, told Healio Gastroenterology and Liver Disease. “RegurgitationRead More

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