Biologic therapy, small molecules induce remission in ulcerative colitis

Biologic therapy, small molecules induce remission in ulcerative colitis

Compared with placebo, most biologic and small molecule therapies correlated with superiority for the induction of remission in moderate to severe ulcerative colitis, according to research published in Gut.“Over the last 20 years novel drugs, with more precise modes of action, based on mechanisms of disease identified in genome wide association studies, have been developed. … In the last 10 years, small molecules, which can be administered orally and on a daily basis, have also been evaluated in moderate to severe UC,” Nicholas E. Burr, MBBS, MRCP, of the Mid Yorkshire HospitalsRead More

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