Childhood antibiotic use linked with appendicitis risk

Use of antibiotics during childhood had a dose-dependent relationship with increased risk for appendicitis, according to study results.“Genetic and environmental factors as well as pathologic alterations of the microbiota in the appendix have been identified as potential risk factors,” Jacob Antonsen, of the digestive disease center at Bispebjerg Hospital in Denmark, and colleagues wrote. “Several studies have shown an altered composition of the microbiota in specimens of appendicitis, but it remains unclear whether the microbial changes are a trigger or a consequence ofRead More

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