‘Downgrading’ acute-on-chronic liver failure improves post-LT survival

Improving acute-on-chronic liver failure grade from time of liver transplant listing to time of transplant enhanced posttransplant survival, especially in recipients older than 60 years.The short-term mortality of patients with ACLF grade 3 (ACLF-3) reaches approximately 80% by day 28, according to Vinay Sundaram, MD, MSc, from Cedars-Sinai Medical Center in California, and colleagues in their study.“In certain patients with ACLF-3, liver transplantation (LT) may be the only viable treatment. However, data regarding LT for individuals with ACLF-3 demonstrates reduced survivalRead More

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