Efruxifermin induces NASH resolution, improves fibrosis by at least 1 stage vs. placebo

WASHINGTON — Efruxifermin improved liver histology, liver fat content and noninvasive markers of disease in patients with stage 2 or 3 fibrosis related to nonalcoholic steatohepatitis, according to late-breaking data at The Liver Meeting.In a previous phase 2a study, efruxifermin (EFX), a long-acting FGF21 analog, reduced liver fat content in patients with stage F1 to F3 NASH and improved noninvasive markers of liver inflammation, injury, fibrosis, glucose and lipid metabolism, Stephen A. Harrison, MD, FAASLD, medical director for Pinnacle Clinical Research and president of SummitRead More

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