Genetic biomarker linking Takayasu arteritis, IBD may guide targeted therapies

When a disease has no clear etiology and no cure — as is the case with Takayasu arteritis — any advance feels like a big advance.Results of a recent genome-wide association study in the American Journal of Human Genetics yielded information that is likely to give patients new hope and researchers new direction: The genetic signatures in Takayasu closely resemble those of inflammatory bowel disease, a much more treatable condition.Patients with Takayasu arteritis experience granulomatous inflammation of the aorta and its major branches that can lead to elevated rates of myocardialRead More

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