Genetics, disease activity impact microbiota in patients with spondyloarthritis

In patients with spondyloarthritis, genetics and disease activity levels likely impact the composition of gut microbiota, according to data published in Arthritis & Rheumatology.“This multifaceted disease is thought to result from complex interactions between genetic background and environmental factors,” Magali Berland, PhD, of the University of Paris-Saclay, in France, and co-authors wrote. “Given that deregulated gut microbial composition, ie dysbiosis, is a hallmark of [inflammatory bowel disease (IBD)], the foregoing observations lend support to the hypothesis thatRead More