Glucocorticoid, proton pump inhibitor use linked to higher osteoporotic fracture risk in RA

The simultaneous use of oral glucocorticoids and proton pump inhibitors is associated with a 1.6-fold increased risk for osteoporotic fractures in patients aged 50 years and older with rheumatoid arthritis, according to data.“The contributors to increased fracture risk include the inflammatory process of RA and the pharmacological treatment of the disease, most importantly oral glucocorticoids (GCs),” Shahab Abtahi, PhD, of Maastricht University Medical Center, in the Netherlands, and colleagues wrote in the Annals of the Rheumatic Diseases. “Patients with RA taking oral GCsRead More

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