Gut-based neurotoxin triggers inflammation associated with Alzheimer’s disease

A neurotoxin derived from bacteria in the gastrointestinal tract has been identified as a major contributor to Alzheimer’s disease, researchers reported in Frontiers in Neurology.The microbial-generated neurotoxin lipopolysaccharide (LPS) is derived from the gut-based, gram-negative bacteria Bacteroides fragilis and creates a pro-inflammatory neurotoxin called BF-LPS, Walter J. Lukiw, MS, PhD, the Bollinger Professor of Alheimer’s disease and professor of neuroscience, neurology and ophthalmology at Louisiana State University, and colleagues reported.“LPSs in general areRead More

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