Ibsrela improves abdominal symptoms in IBS-C

Ibsrela helped reduce abdominal symptoms, like bloating, cramping and fullness, in patients with constipation-predominant irritable bowel syndrome, according to study results.William D. Chey, MD, director of the GI Physiology Laboratory at University of Michigan Health System, and colleagues wrote that Ibsrela (tenapanor, Ardelyx) is a first-in-class, minimally absorbed, small molecule inhibitor of the gastrointestinal sodium/hydrogen exchanger isoform 3 (NHE3), which helps maintain salt and water balance through the electroneutral exchange of intestinal sodium ions for intracellular protons.“NHE3Read More

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