Impaired humoral, upheld cellular responses in patients with IBD after SARS-CoV-2 vaccine

SAN DIEGO — Though patients with inflammatory bowel disease have impaired humoral response after SARS-CoV-2 vaccinations, cellular responses were maintained and comparable to those of health care workers, according to study results.“We believe that the results of our study are overall reassuring and provide mechanistic explanation for the lack of higher COVID complications in our patients with inflammatory bowel disease, particularly with the fact that antibodies in all of our analyses were well above the positivity threshold, and that overall [T-cell receptor (TCR)] metricsRead More

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