Lubiprostone safety profile comparable in children, adults with PFC

Lubiprostone safety profile comparable in children, adults with PFC

Lubiprostone was not significantly more effective compared with placebo in children or adolescents with pediatric functional constipation; however, the safety profile was similar to that in adults, according to study results.“In summary, the results of this analysis of two phase 3 studies showed that the overall safety profile of lubiprostone in this population was comparable to that observed in adult patients with chronic constipation,” Marc A. Benninga, pediatric gastroenterologist from Emma Children’s Hospital, Amsterdam University Medical Center, the Netherlands, andRead More

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