Multitarget stool DNA has high positive predictive value in CRC

Non-invasive screening with multitarget stool DNA tests had a high positive predictive value for any colorectal neoplasia regardless of a patient’s exposure to previous colonoscopy, according to study results.John B. Kisiel, MD, of the division of gastroenterology and hepatology at Mayo Clinic in Rochester, Minnesota, and colleagues wrote that multitarget stool DNA (MT-sDNA) testing amplifies methylated BMP3 and NDRG4, mutant KRAS and beta-actin and measures hemoglobin through immunochemical testing.“MT-sDNA utilization has increased substantially since its approval and subsequentRead More

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