‘No evidence’ antibiotics prevent hospital-acquired infections in cirrhosis patients

Antibiotic prophylaxis failed to reduce the incidence of hospital-acquired infections or overall mortality among patients with decompensated cirrhosis, according to data published in The American Journal of Gastroenterology.“We undertook this study as we were struck that clinicians in our large-scale trial Albumin to Prevent Infection in Chronic Liver Failure (ATTIRE) prescribed antibiotics to more than 50% of patients at hospitalization even though they only thought 27% had an infection,” Alastair O’Brien, MBBS, BSc, FRCP, PhD, professor of experimental hepatology andRead More