Opioids linked with hepatic encephalopathy in patients with cirrhosis

Opioid prescriptions were associated with a risk for hepatic encephalopathy in patients with compensated cirrhosis, according to study results.Andrew M. Moon, MD, MPH, of the division of gastroenterology and hepatology at the University of North Carolina at Chapel Hill, and colleagues wrote that opioids could potentially contribute to risk for HE in these patients, but current research has returned conflicting results.“Opioids could lead to altered gut microbiota, upregulation in central mu-opioid receptors and slowed intestinal motility, which could increase intestinal absorption ofRead More

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