‘Phenotype-informed interventions’ hold key to treat obesity, break weight cycling

Although an estimated 45 million Americans will try a diet each year, roughly 90% of people who lose weight end up gaining it back.This perpetual diet, weight loss and weight gain cycle can be discouraging for people who want to successfully lose weight and improve their health, but there are significant metabolic adaptations at play that influence a person’s ability to maintain their weight loss.Obesity is a disease of energy balance dysregulation that results in the storage of excess calories as fat. Energy balance relies on energy intake and expenditure; two processes tightlyRead More