Q&A: In utero exposure to Bendectin linked to increased risk for CRC in adult offspring

Prenatal exposure in the 1960s and ’70s to dicyclomine, a component of the anti-nausea drug Bendectin, increased the risk for colorectal cancer in adult offspring, according to data reported in JNCI Cancer Spectrum.“In the 1960s, Bendectin (doxylamine/pyridoxine/dicyclomine) was frequently prescribed to pregnant women to manage nausea and vomiting. Bendectin was initially approved in 1956 and quickly became the most common treatment for nausea or vomiting of pregnancy in the U.S as its use grew in the 1960s and ’70s,” Caitlin C. Murphy, PhD, MPH, associate professor atRead More

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