Signaling pathway ‘key needle within the haystack’ driving Barrett’s, esophageal cancer

Researchers have identified a cell signaling pathway involved in the development of Barrett’s esophagus and esophageal adenocarcinoma, which may lead to possible life-saving therapy for this aggressive cancer.In a study published in Gastroenterology, Kishore Guda, DVM, PhD, associate professor at Case Western Reserve University School of Medicine and Case Comprehensive Cancer Center, and colleagues performed whole transcriptome RNA sequencing in primary Barrett’s esophagus (BE), esophageal adenocarcinoma (EAC), normal esophageal squamous and gastric biopsy tissues and found thatRead More

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