Testosterone in premenopausal women with NAFLD linked to higher risk for NASH, fibrosis

Young women with nonalcoholic fatty liver disease had higher testosterone levels, which led to a twofold higher risk for nonalcoholic steatohepatitis and fibrosis, according to study results.In addition, the higher testosterone levels increased the risk for abdominal adiposity, supporting a potential mechanistic link of abdominal fat on testosterone-associated liver injury.“Testosterone may represent an early risk factor for NASH progression in young women, prior to their onset of more dominant, age-related metabolic risk factors,” Monika Sarkar, MD, MAS, from the University ofRead More

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