TNF inhibitors less effective for older-onset IBD patients

Anti-tumor necrosis factor therapy had reduced efficacy and safety for bio-naive patients with older-onset inflammatory bowel disease compared with younger patients, according to a study published in Scientific Reports.“Anti-TNF treatment is effective for both the induction and maintenance of patients with IBD and improves their quality of life. The efficacy and safety of anti-TNF treatment for [elderly onset IBD (EO-IBD)] are not yet clear, however, because elderly patients are generally not included in large-scale studies such as randomized controlled trials,” Takahiro Amano, ofRead More

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