Tumor rupture linked to worse outcomes among patients with GIST

Tumor rupture appeared associated with shorter OS among patients treated with or without imatinib after surgery for gastrointestinal stromal tumors, or GIST, according to results of a post-hoc observational study published in JAMA Surgery.However, researchers found no association between microscopic margin status without tumor rupture and shorter survival.“It was not clear how to interpret the presence of a positive microscopic margin on the surgical specimen of a resected GIST, which was the implication for management as few data were available and conflicting,” AlessandroRead More