UDCA response linked to mortality in primary biliary cholangitis with cirrhosis

In a cohort of predominantly men with primary biliary cholangitis with cirrhosis, ursodeoxycholic acid response correlated with a decrease in decompensation, all-cause, and liver-related death or transplantation, according to study results.“The benefit of UDCA response seems to be the highest in subjects with portal hypertension,” Binu V. John, MD, MPH, from the division of hepatology, Bruce W. Carter VA Medical Center in Miami, Florida, and colleagues wrote. “Future studies are needed to evaluate if newer agents, such as obeticholic acid and the fibrates, can improve theRead More

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