Vancomycin with SER-287 more effective vs placebo for remission in UC

Investigators found vancomycin preconditioning followed by SER-287 was significantly more effective compared with placebo for induction of remission in patients with active mild-to-moderate ulcerative colitis.“SER-287 may represent a new therapeutic paradigm for UC with potential advantages with respect to safety and convenience of oral-dosing,” Matthew R. Henn, MD, from Seres Therapeutics in Cambridge, Massachusetts, and colleagues wrote. “Based on these results, daily SER-287 following vancomycin preconditioning is undergoing further evaluation in a phase 2b trial.”Read More

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