Tacrolimus shows promise in treatment of dermatologic conditions with risk factors

Compared with the systemic calcineurin inhibitor standard cyclosporine, tacrolimus shows promise for numerous dermatologic conditions, whereas the literature on voclosporin is limited, according to a study.“Systemic calcineurin inhibitors (CNIs), cyclosporine, tacrolimus and voclosporin, are immunosuppressive drugs commonly used in organ transplantation,” Annie Dai, MD, and Soo Jung Kim, MD, PhD, both of the department of dermatology at Baylor College of Medicine, wrote. “CNIs’ main immunomodulatory mechanism is inhibiting interleukin-2 and disrupting T-cell activation.”Read More