Two-step Clostridioides difficile testing was associated with decreased reported incidence of hospital-onset C. difficile infection and C. difficile-specific antibiotic use, researchers found.“Two-step testing has made some clinicians nervous that they might miss or delay C. difficile diagnosis in patients who are nucleic acid amplification testing positive/toxin negative (colonized),” Nicholas A. Turner, MD, MHSc, assistant professor in the division of infectious diseases at Duke University Medical Center, told Healio.“While there have been several previous individual-levelRead More
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