Chemotherapy plus durvalumab combinations show promise in advanced biliary tract cancer

Chemotherapy plus durvalumab combinations show promise in advanced biliary tract cancer

Gemcitabine and cisplatin plus durvalumab, with or without tremelimumab, produced favorable outcomes as first-line treatment for advanced biliary tract cancer, according to research.“Immune checkpoint inhibitors have been assessed in biliary tract cancer and have shown clinical activity,” Do-Youn Oh, MD, of the division of medical oncology at Seoul National University Hospital, and colleagues wrote in…

Study confirms malabsorption is a sign of celiac disease

Study confirms malabsorption is a sign of celiac disease

A large observational cohort study conducted in Copenhagen confirmed that malabsorption is associated with celiac disease, according to researchers.The findings were published in Scientific Reports.“This study identified several biochemical abnormalities associated with celiac disease (CD) antibody positivity in a primary care setting among individuals referred to CD antibody testing,” Line Lund Kårhus, MD, PhD, the…

FDA grants priority review to Imfinzi with chemotherapy for advanced biliary tract cancer

FDA grants priority review to Imfinzi with chemotherapy for advanced biliary tract cancer

The FDA granted priority review to durvalumab plus chemotherapy for treatment of locally advanced or metastatic biliary tract cancer.Durvalumab (Imfinzi, AstraZeneca) — a PD-L1 checkpoint inhibitor — is approved in the United States for treatment of patients with unresectable stage III non-small cell lung cancer whose disease has not progressed after chemoradiotherapy. It also is…

FDA approves two vonoprazan treatment regimens for H. pylori infection

FDA approves two vonoprazan treatment regimens for H. pylori infection

Phantom Pharmaceuticals Inc. has announced FDA approval for its Voquezna Triple and Dual Paks for the treatment of Helicobacter pylori infection in adults.According to a press release, the new drug applications for Voquenza Triple Pak (vonoprazan tablets, amoxicillin capsules, clarithromycin tablets; Phantom Pharmaceuticals) and Voquenza Dual Pak (vonoprazan tablets, amoxicillin capsules; Phantom Pharmaceuticals) were given…