Anti-TNF, surgical closure induces long-term healing in Crohn’s fistulas

Short-term anti-tumor necrosis factor treatment combined with surgical closure induced long-term MRI healing in patients with Crohn’s perianal fistulas more frequently than anti-TNF therapy alone, according to research.“Management [for Crohn’s perianal fistulas] remains challenging and the most optimal treatment for Crohn’s high perianal fistulas with a single internal opening is still undetermined,” Elisa M. Meima-van Praag, MD, of the department of surgery at Amsterdam University Medical Center, and colleagues wrote in The Lancet Gastroenterology & Hepatology.Read More